wikipedia wrote:
Lain is influenced by philosophical subjects such as reality, identity, and communication.[2] The series focuses on Lain Iwakura, an adolescent girl living in suburban Japan, and her introduction to the Wired, a global communications network similar to the Internet. Lain lives with her middle class family, which consists of her inexpressive older sister Mika, her cold mother, and her computer-obsessed father. The first ripple on the pond of Lain's lonely life appears when she learns that girls from her school have received an e-mail from Chisa Yomoda, a schoolmate who committed suicide. When Lain receives the message at home, Chisa tells her (in real time) that she is not dead, but has just "abandoned the flesh", and has found God in the Wired. From then on, Lain is bound to a quest which will take her ever deeper into both the network and her own thoughts.